I would suggest enabling UAC and Smartscreen as you having nothing to lose but everything to gain.
As @frogboy said, use some kind of backup, there are many free products to chose from so again you have nothing to lose.
Unless you can afford to lose everything on your computer, not having backups is just asking for trouble.
Enable UAC to at least default.
You could probably benefit from another on demand scanner such as Zemana Antimalware.
Consider some type of Data & System back up solutions.
Infection within the last 3 months?
Thanks for sharing your config