no when DR WEB Preventive protection is set to "paranoid" mode it kills/prevents loading of 3 rd party application drivers . this may cause failure .
However i don't know if it set to default levels.
But in both levels, if u can will to allow manually each time dr WEB asks you..then may be it sets well
i don't see why it wouldn't. malwarebytes is developed to run complimentary. that said, i'm sure you could add an exception to dr. web for mb. if you find the two a bit heavy, you can turn off the real time scanner for mb and keep all the supplementary protections.