Websites have no problem working and resizing on all size displays (Responsive design), from flip-phones to 60" 4K TVs.Nonsense. My concept for example has the size that fits even on 800x600 resolution. Tell me, when will you need to use interface on anything that small or smaller to have a need for resizable GUI? Besides, resizable interface can bring so many problems it's just not worth it. As we've seen with avast! 17 launch, 1024x600 netbooks are the main issue currently. 800x600 compatibility is being very generous at this point...
When there is a list for me to go through, I don't want to thumb through a few lines at a time (list of suspicious files, logs, etc.).
Avast actually does a good job with resizing and with lists and with the gajoodles of options it has; I can resize X & Y, vertically maximize, etc. like a window should do.
AV/Security software is notoriously bad about UI/UX; if you want to separate from the pack, put effort into the man-machine interface rather than making it look flashy/glitzy/crazysexycool at the expense of usability. Create both.
To evaluate the design you have, include the OFF color/all colors of your palette.