Why I only have two. Plus you never know if one is truly fully compatible with the other and so maybe rendering them both only partially functional... you think a feature is doing something but it's actually not... both are partially blocking the other. These programs have to access special key areas of your computer to shield these components. I do know that Bitdefender states that it won't install if Webroot is installed.Removed Avast & Adguard for now. I am so used to these extremely light anti-exe/whitelisting/virtualization apps, when I install an AV I notice the change in responsiveness very easily and it drives me nuts! I think for now I'll stick with my current config and maybe install HMPA here soon.
Voodooshield is an exception. I do notice a change in responsiveness when it's installed
A friend has told me that malware and phishing sites these days are sophisticated enough to detect whether a request comes from a VirusTotal server or not, so the user is served the malware while VirusTotal is served a clean website.you can always scan the URL with services such as Virus Total.