I am not a fan of combo and I wonder why people think of using such combos. I believe this causes a higher system impact than running a one suite would cause. Compatibility issues are expected when running such combos. I am not a security expert but other more advanced members might give their opinions.
It seems that you have misunderstood me. I was speaking in general that using combos pose a higher risk or incompatibilities and might cause a system impact. That's why I prefer to stay away of running combos.