I did test both tweaks, but I prefer Wise Care's actually because it's less involved, and the system default is really easy to bring back in one click on the bottom right. Nice subtle improvements.
Tweaking.com is more advanced and intimidates me so I only viewed the tweaks
Everyone on malwaretips probably really looks after their PCs well being, and wouldn't need to tweak, but to add more memory, card, or buy better hardware.
Since I re-install Windows... I don't need any tweaks really. No regisrty cleaner anymore or anything besides Wise Care and CCleaner for junk deletings.