Shmu- I'm SOOO glad you asked that question, and please allow me a long-winded and overly complicated (as usual) response:
1). UIWIX in particular will check for the presence of the Comodo Sandbox (Containment), and if detected will shut down. So what does this mean to a CF user on a real system? The file will just shut down and not run. This means for a Comodo user to be infected by UIWIX they would have to uninstall Comodo, reboot, then run the malware. It is my fervent hope that ALL malware would have such Comodo checks!
2). I hope that it isn't needed for me to speak again about how CF handles ransomware other than to say it blows it off.
3). The worm-like activity of UIWIX- this is a topic that I've been ranting on for the past few years, and until this month no one has given a flying(add curse word here) about. At my settings (as I have shown in past videos), CF deals with worms and worm-like activity the same way it deals with ransomware. It stops it.
Worms and those malware that will exhibit worm-like activity have always been a Clear and Present danger to the computer user. Almost totally ignored by everyone else, it gladdens my heart that it is finally being given the significance that is needed. Now if only the majority of Security vendors will actually ACT on this problem instead of the typical dismissal the world will be a happier place.
Comodo has already long since had such protection, but is it is like they are a Voice Crying out in the Wilderness...