I've been using Dr.Web for past week as trying to decide which to use for Windows 10 and I find it to offer great protection, with minimal resource usage. I enable parental control as the IT dept. at our hospital said they use it, and it stops a lot of dangerous websites. Comodo's antivirus to extremely poor, yes, the sandbox, firewall etc., is okay, but Dr.Web has preventive protection which stops software accessing critical system files; set this to medium or paranoid and (I would think) nothing could get through.