Are you updated to the latest Windows 10 stable build?
You should seriously consider some type of system & data backup solution.
Both Macrium Reflect and AOMEI Backupper offer good free programs.
You should enable Smartscreen.
Consider an additional on demand scanner(s)
Consider uBlock Origin in place of AdBlock
Thanks for sharing your config
Go to control panel>System and Security>System maintenance
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Go to settings>Privacy>General
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