Hi Ajay123,
Give it a try. If you already having your favourite antivirus, you can install the No Offline Antivirus version.
The application whitelisting will guarantee you from malware infection, either known or unknown malware.
Due to the amount of malware generated daily, it is impossible for AV vendor to detect all.
So you will need another layer of protection.
SecureAPlus. Block All Malware. Guaranteed.