I wouldn't use two anti-malware programs with activated realtime-protection at same time/on same system!
One Anti-Malware with a good signature -and cloud-detection is more than enough in relation to anti-virus realtime-protection.
In addition it would be more efficient to use an anti-exploit, sandbox, anti-executable program.
For example my Realtime-Protection-Setup:
Kaspersky Anti-Virus for realtime-scanning with Anti-Exploit/Behavior analysis against malware.
HitmanPro.Alert with Behavior analysis/Exploit-Protection, Keylogger-Protection, Safe-Browsing, Bad USB (and and and...)
VoodooShield Pro (or Premium?) which prevents principle every file to run! You need to accept manually and it shows a virustotal analysis.