Security software-wise, you are all good.
As
@JM Security suggested above, you do not require both Adblock Plus and uBlock Origin (they do exactly the same thing, having them both on just consumes resources in your system and probably makes your browsing slower).
uBlock Origin is much simpler, more modern, and faster than Adblock Plus.
Make sure you use Windows Backup to create a system image of a known safe state of your system, so that you can restore it to that exact state in case of a software disaster (malfunction or infection).
That would be all. Other than this, you are good to go.
Thanks for sharing your config with us.