Thanks, [USER=89179]@Minimalist[/USER] for posting the ESET forum link.From what I read in the forum, I believe there was some change in the recent v16.0.22.0 update and after that it started to generate some conflict, when keepass is opened in secure desktop, it stays in loop. Wait, [USER=61091]@simmerskool[/USER],they have created a ticket for further investigation by the developers.