very nice config and thanks for sharing. my suggestion is to add a second browser just to be sure,an on-demand scanner except eset like malwarebytes free or emsisoft emergency kit.also i recommend to add a password manager like lastpass or dashlane to secure your passwords when you are online
Personally I would not use TUU.CCleaner is more than enough
I would go with a free backup solution as there are many good free ones
I would also recommend a password manager as well as a couple more on demand scanners
Add HTTPS Everywhere to FF
Thanks for sharing your config
Looks good, but I don't know what to think about : Advanced System Care, IObit Malware Fighter, Advanced System Optimizer, Driver Updater - None of these programs are worth using.