Yeah that’s a really good point. F-Secure has like 5 separate modules including dedicated certificate reputation and script scanning engines, plus DeepGuard is some weird hybrid between being a heuristic analyzer, BB, HIPS, and cloud reputation engine. It seems like they would likely have less reliance on signatures from their classic AV engine.
The other thing is all these engines makes update speed a big concern for F-Secure. That is probably the reason why they like Avira and their cloud based approach. Even DeepGuard has a signature database — in the BD days it would take forever to do the initial update after an install.