Derwan, I ll try to answer some of your questions based on my case.The main reason why I stopped using an antivirus is because I am safer not using one. I want to avoid conflicts, I want SBIE to be at its best at all times, I don't want to water down Sandboxies protection, not having anything else that's exactly what I am achieving.
Additionally, my computers feel better without one. I remember I use to hear noises coming from the inside of the PC, that doesn't happen anymore, I believe by not installing/uninstalling antiviruses, other security programs or running scans my computers will last longer. It is cause and effect (less work, PC healthier). My computers don't suffer lags or freezes when opening a folder or a file. They open automatically. unlike when using certain antiviruses. I read all the time about people suffering a BSOD after an upgrade, I don't go through any of that. Upgrading my AV use to give me stress, no more. My stress level when using an AV was about 8, without one is down to 1. Thats how good it feels not using one.
Most antiviruses work well with Sandboxie in the surface, they appear to work well but we never know whats going on between the two underneath. In my case, I don't want to wait to find out when I get hit by malware to see if SBIE and the AV were able to behave as they are supposed to. They might or they might not. I don't want that chance.
For people that see Sandboxie as a browser in a sandbox, if your default sandbox opens and closes slow, it might not be a big deal but if you are using the paid version, using multiple sandboxes, I got 14 now in this PC, this is important. Some antiiviruses, HIPS and Firewalls keep a lock in your programs and files when you run them sandboxed and the sandbox might take a few seconds to open and close. I don't want any of that. I want my sandboxes to open and close immediately with no delay and that's how it is here.
Is easy to know if someone should not drop using an antivirus. If you stop using one and you have the urge to do scans or "feel naked", then you are not ready. If you feel insecure, then you are insecure and you are not ready. If at any time you have doubt about whether your PC is clean or not, you are not ready. Is easy to know.
Bo