Second opinion scan is OK and all, but what if it doesn't detect anything because it has no signatures to detect with ?
It is better testing methodology to manually inspect what is running in active memory using Process Explorer, Process Hacker, System Explorer, etc. If you find something, then you can check for its autorun.
Also, check if anything placed inside Documents\My Private Folder or any other user-created Private Folders has been encrypted.
If anything else in User Space is encrypted - it isn't important - because after a ransomware infection, you will need to clean install the OS to start over with a known clean system.
The goal of AppGuard Private Folders is to protect user data - and that's it - but a user has to take full advantage of Private Folders.
Yes if it's Guarded. But you have to manually put it into Guarded list to do this, as Locked Down mode just blocks its execution. So, why would you put it into Guarded list in the first place?
Protected mode, at this time, does not block the execution of files with a proper certificate. However, the digitally signed ransomware would have to encrypt connected drives and specifically the Macrium image file type.
All this matters if you are paranoid. In that case, don't leave any external drives connected to the system all the time.