for register maintenance does ScanMyReg 2.2 good app to have - there is giveaway choose from app and i compere witch app to have and this one in the list -
ScanMy Reg has issue with false positives, which means it may delete some needed regustry keys. As a result I highly recommened that you don't use it. Also, it's important to understand that you never actually need to perform any registry maintenance. Windows has designed the registry in such a way that excess registry keys won't slow down your system. In actual real world usage, it is exceptionally rare for a registry cleaner to speed up your computer. Also, it's almost just as rare for cleaning the registry to actually fix any issues you have with your computer. A registry cleaner may find, hundreds, or even thousands of so called errors, but 99.9 percent of the time, they simply do no matter, and won't be slowing down your computer or causing problems. To make matters worse, almost all registry cleaners (even well known and trusted ones) will delete needed registry keys. Even the registry cleaner in CCleaner has very occasional issues with false positives.
With regard to the other programs you mentioned. You say, that you saw no affect after running them. Were you trying to make your computer faster, or fix problems? Software like these are not always going to make much of a difference in system performance. Also, Wise Care has occasional issues with false positives, which means occasionally it may delete needed registry keys. However, Advanced SystemCare and WinOptimizer are both safe to use. If you are running them to try and fix problems, it's rare for tools like these to ever fix any problems. If you have problems with Windows, then I highly recommend using
Windows Repair from tweaking.com, as it can actually fix a lot of issues with Windows.
Kerish Doctor works very well, and the trial version is fully functional, so you can try it and see if it helps. Also, it has the benefit that it can actually fix some problems.
If your computer is running slowly, there are few things to consider which may be slowing it down:
Security software. Some antivirus software will cause very noticable slowdowns on some systems (which you can fix my switching toa different antivirus). Also, for the most part, you should never have more than one antivirus installed. What antivirus are you running?
Not enough RAM. You usually need at least 4GB of RAM installed. How much RAM does your computer have?
Also, your computer will run a lot faster if you replace your hard drive with a SSD.
