Best ransomware blocker based on zero day feedback

If you are medium-advanced user and are willing to learn:
- Free: anti-exe (voodooshield, novirusthanks ERP), comodo firewall
- Paid: appguard

If you are an average users and don't want to deal with popups/prompts everyday:
- Free: kaspersky free or kaspersky security cloud free
- Paid: kaspersky, emsisoft

or a combo between 1 AV and dedicated antiransomware tool like appcheck antiransomware free

Kaspersky free/paid is the best AV against ransomwares according to several tests in all conditions. No other well-known AV is better
 
Why not adding a Anti-Ransomware solution next to the AV of your choice?

I would recommend CheckMAL AppCheck AntiRansomware Free, it comes with Behavior Blocker, Auto-Backup (limited to preset), Remediation of affected files, MBR Protection.
Free and efficient against most ransomware.
Make sure to have a backup anyway in case a malware of a system / hardware failure cripples your system. Don't attach the external HDD to your running system unless performing / restoring from a backup, it will be targeted by malware otherwise.
Product Introduction - CheckMAL
Thanks for this tip @Der.Reisende , looking forward to trying (y)