Non profits , schools and some enterprise use their enterprise product because they claim 100% bs and are cheaper then any alternative
I really like the idea of not full virtualization that comodo does because it uses less performance then virtualization but both their container can be escaped and trusted dlls ,exes ( trusted lolbins) are automatically run without containment while unlike Kaspersky , other av software it doesn't have good behavior detection to help against a bypass as viruscope is awful
I'm still using comodo on most my PCs (usually as a layer) so some bypasses might be stopped by either hitmanpro.alert or ESET on my system or checkpoint threat emulation that I have in the browser extension so I'm safe against 99.99%+ and I usually submit suspicious files to Broadcom before running them using
Sample Submission | SymSubmission
But hopefully one day I could use only comodo comfortably if they do improve it as comodo has excellent performance usage and I have one low end 2gb ram with emmc laptop that can't run ESET on it without performance issues nor defender and comodo didn't seem to slow io , use much ram and it's a gift to low end machines making them mostly secure while not having to go chrome os route or any too restrictive policy config
So I definitely find comodo very useful and because it's not perfect if anyone uses comodo use it as a layer if possible with some free av (Kaspersky free, defender , bitdefender free ,avast free etc )