Hi,
First of all , you should remove MSE, yes it sound excessive but the product is so slow and inefficient that using it is a opened-door to malwares.
check this
review done by our main reviewer
if you want a free solution, rather use Avast, Avira, Panda Cloud AV, Comodo IS or other.
you can keep Tinywall with Win7 firewall.
Your On-demand scanners are good (note: Ccleaner and Defraggler are not O-D scanners just maintenance tools), you can add Hitman Pro or Comodo Cleaning Essentials as O-D scanners.
Do you use any backup softwares? (sorry Malware Maniac & McLovin
)