One of us can check your computer over for you if you like?
If you can
download FRST from
here and save it to your Desktop. Then open the tool and press the
Scan button. You'll then find two log files on your desktop, called
FRST.txt and
Addition.txt if you could reply back to this thread with both of those files attached using the
"Upload a File" button (next to "Post Reply"), I will check everything over and if necessary give you further instructions on cleaning up your computer
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Edit: I would recommend dumping Adblock Plus for
uBlock which is much lighter on your system and faster
Other than that, your setup looks good, although I'm not sure you need so many different on demand scanners
And as Illumination points out below, having a backup solution is a must. If you don't use backup software, do as I do and copy your files onto CDs, DVDs or some kind of once-writeable media for permanent backup.