do you compare Emsisoft AM against Kaspersky AV or IS?
if Kaspersky IS , then you should compare it with Emsisoft IS (EAM + OAP)
In that case, Emsisoft all the way...but i am not impartial, i dont like KIS and i love Emsisoft
more seriously:
In detection they are quite similar after some tests done here in the malware hub, KIS is known for its very good detection, Emsisoft uses its own engine plus Bit Defender one; so for me it is equal.
In prevention, KIS has a strong webfilter, HIPS and banking mode but Emsisoft has the best Behavior Blocker and HIPS on the market, so i will say Emsisoft in term of prevention.
i suggest to test the trial of both of them, then you will have a better feedback, remember that every system is different so what is true for me may be different for you.