Regarding CCleaner.
Potentially unsafe applications is the db that flags tools like CCleaner.
I don't use potentially unsafe detections because i am an experienced user.
However if i was installing ESET on someone who knows nothing about computers, ie an elderly individual (have seen this in the field, and its just an example)I would use the detection.
Having the detection on, is not primarily for CCleaner which is a good tool, but it may keep dumb and fake computer cleanup tools that have no business being installed.
If you can think of a way to separate the two and have the detections still on, please share with us and the ESET developers.
You can take a very good program like CCleaner which gets flagged because of google chrome, and remove the detection for Googles dll's, exe, and embedded toolbars, however while you are removing the detection that blocks CCleaner, you are also removing it from a very bad piece of software as well ? You can't win and you can't lose.
That is why there is an exclusion portion in the software and the ability to turn off 'potentially unsafe applications'.
Normally i would say it should fall under
Potentially Unwanted Applications detection, however those are more severe than unsafe, and Google toolbar or chrome doesn't belong in that category.
However i have seen malware writers, manipulate, alter code, and use Google's stuff to embed some serious changing objects to the OS, example: A Fake google toolbar.
If you are truly, truly, interested in understanding what causes a program to fall into the potentially unwanted, have a read through this article:
Potentially unwanted classifications
So going back to this statement:
"ESET said Ccleaner infected with PUP, i scanned it & it totally remove CCleaner to quarantine. I guess, there is anyway they can cure it rather then clean it."
It's not a PUP (the default name for potentially unwanted), but a different classification "potentially unsafe".
To answer the question, you need to disable PUsA, there is no way to cure it. ESET won't separate the two for you.
Here is a link to Wilders where Aryeh the distinguished researcher at ESET, who was the first employee at McAfee, years and years in the business, talks about the two detections. :
Link
Its back from 06, and we have had many many changes since, but it is mostly still the same.
Here it makes it seem as if Ccleaner should fall into unwanted category, and i might ask some of the developers and ESET reps why its labeled under unsafe, and i presume its as i stated, its not as threatening as a potentially unwanted application, plus it will notify you of the Google chrome installation if you don't have it installed yet.
Thanks for reading.