i think you need to try Eset or Emsisoft.
I dont know how well you are aware of the internet threats, but using common sense will save you most of the times.
I have used Eset, Emsisoft, Avira & Kaspersky in the past so i can talk only according my experience.
Kaspersky seems to be a little heavy but it does well in the detection/disinfection area. Kaspersky has this great ability to disinfect infected files and this can be very useful if for example an important system file is infected.
Avira is also good but my opinion is that it is an overated product. It's doing well but it was never my favorite. It is buggy sometimes and this ''system is being scanned'' everytime it finds a virus can slow down your pc.
Emsisoft is using 2 engines (Emsisoft & Bitdefender). It is a very simple product to use, very effective, and with a great support team. I'm sure you will find Emsisoft's behavior blocker very useful. In my case it caused a huge slow system start up and high memory usage.
Eset will be my top choice as it is very light on the system (and believe me i do crazy things with my pc). It's detection rate is awesome, and in my opinion, the best among other paid products. Eset also release very frequent updates to detect even 0 day threats. It's among the first companies who correspond faster to 0 day threats. Their support team is also great.
According your experience and computer specifications is always better to ''try before you buy'' It is the only way to find out what product really meet your needs.