I wouldn’t run Malwarebytes Premium alongside BD personally. I have a license, but since the 4.0 update it slows performance more than it used to. Especially file transfer speeds. BD finally got light, they have great web protection already, and exploit protection, better ransomware protection than MB, no need to slow it down. If you want something to run with BD I’d recommend NoVirusThanks OSArmor, or VoodooShield. Neither have much impact on performance. VoodooShield will slowdown apps on their first launch, but not after they are whitelisted.