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While on the subject of configuring Application Control: it is best not to modify it any more than necessary, but I do think it's good to move the 4 powershell processes to Untrusted. That way, even if they get launched via dll or other tricks, they still will not be able to do anything.
The .dll is self-contained and does not rely upon the powershell shell being enabled. In other words, moving them to untrusted is not going to stop powershell from running on the system. Depending upon the type of attack, it could be in-memory only or malware can supply its own self-contained version of powershell that does not require anything that is shipped on the system.
Plus, there is a toggle switch so there is no need to move to Untrusted.
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