FWIW I'm running ESET NOD32 17.0.15.0 and I implemented its HIPS interactively after letting it Learn my win10_VM for +10 days then set it to "interactive" and it is working nicely, not too intrusive, and so far the HIPS alerts are easily understood, the first alerted to chrome accessing its helper to do something benign, 2d alerts was for keepass accessing browser to input URL. In past I never really played with ESET HIPS leaving it at default. Liking interactive for the time being, an occasional alert lets me know it's working... 