Not able to update nod 32 online scan & malwarebytes

Can you post a screenshot?

If you're using a direct connection, uncheck ESET Online Scanner to connect via a custom proxy.

It's possible that Bitdefender may not be allowing ESET or Malwarebytes to connect to the Internet, can you check it's Firewall settings?
 
now eset online scan is running fine .Malwarebytes is also working fine..Dont know what happened until now will post here if i face any new problems..:D
 
Can any one let me know those registry entries are safe or should i need to delete any one ? Panda cloud online scan is showing it in suspicious files list so i want to make sure i want to delete the right one..Cucusoft is ok its just bandwidth monitor software but the remaining registry keys i am not able to understand..[attachment=4359]
 

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That can be malware-related as for example, this one will change the value to 1: https://www.microsoft.com/security/portal/threat/encyclopedia/entry.aspx?Name=Worm%3AWin32%2FAutorun.CF

Did you set the policy to hide file extensions?