Real Time Protection:
Did you change any other settings in the Comodo Firewall? You can use this guide to improve the protection from the COMODO Firewall - http://malwaretips.com/Thread-Guide-on-how-to-install-and-configure-Comodo-Firewall
You have a good config but it's based only on prevention so I would recommed that you add an antivirus engine to your setup as your Risk level is set to 'High'.
Additional browser protection:
WOT (Free) -
link
To help you avoid malicious sites you can use Web of Trust (WOT) a website rating browser plugin. After you add it to your browser make sure you only visit websites rated "Green" by WOT
LastPass (Free) -
link
LastPass is an online password manager and form filler that makes web browsing easier and more secure.
Virtualization:
I'm sure you've heard about Sandboxie and now that it works decently on 64bits maybe you should give it a try...
Sandboxie (Free/Paid) -
link
Sandboxie runs your programs in an isolated space which prevents them from making permanent changes to other programs and data in your computer.
+1 for backing up .. overall you have a good config ..Stay safe!