Be sure to enable "Application Control" in Panda Dome which is usually very effective with unknown exe malware, also Data Shield (but may fail protecting data against ransomware), on the other hand I would pair it with NVT OSA, or apply NVT SysHardener (Suggested Tweaks good enough) to mitigate scripts attack vector where Panda Dome is quite weak...
Remove Panda Dome as
Virus and Malware Removal Tools, since it is already Your real-time protection, here I would consider HitMan.Pro Free, Norton Power Eraser and MalwareBytes Free...
I would also consider to run backups of important data to external devices.
Thanks for sharing