I would add on demand scanner, Zemana, Malwarebytes and perhaps the Emsisoft Emergency Kit, I would trade Adblock Plus by uBlock Origin or AdGuard Ad Blocker
I recommend you enable User Access Control, it is vital to Windows protection. I would also look into OS App Reputation, Windows 10 does have SmartScreen available system-wide, not just IE like in the past. As @Jrs30 said, swap out Adblock Plus for uBlock Origin, it is much more responsive on page load speeds.