Real-time protection
Looks good , ESS 5 has a very good detection rate , this and Sandboxie should give you a high degree of security, nevertheless
common sense is always need it.
Additional on-demand scanner:
Hitman Pro (Trial) -
link
An on-demand scanner using multiple anti-malware engines and cloud technology. It offers unlimited free scanning but once you use it to remove detected malware it switches to a 30-day trial version. I recommend using it after you've scanned your hard-drive with the other products you have installed.
Additional browser add-ons:
Here are a really must have/try addons for your browser , they will make your life easier and safer :
WOT (Free) -
link
To help you avoid malicious sites you can use Web of Trust (WOT) a website rating browser plugin. After you add it to your browser make sure you only visit websites rated "Green" by WOT
VTzilla (Free) -
link
VTzilla is a Mozilla Firefox browser plugin that simplifies the process of scanning Internet resources with VirusTotal. It allows you to download files directly with VirusTotal's web application prior to storing them in your PC. Moreover, it will not only scan files, but also URLs.
The scanning options are embedded in Firefox's context menu and download dialog, making the analysis process as easy as clicking a single button.
LastPass (Free) -
link
LastPass is an online password manager and form filler that makes web browsing easier and more secure.
Extra protection:
EMET 2 (Enhanced Mitigation Experience Toolkit) (Free) -
link
EMET provides users with the ability to deploy security features built into Windows to arbitrary applications. This helps prevent vulnerabilities in those applications from successfully being exploited. DEP, SEHOP and ASLR are such security features, if you want to learn more about what they do, you can watch this
video from Microsoft TechCenter. To configure EMET you should follow this
guide by rationallyPARANOID.
Also you can try
Personal Software Inspector (PSI) from Secunia instead of CNET Tracker , as I'm sure it will do a better job at detecting out-dated software.
And because you are and Advanced User you can try
COMODO KillSwitch instead of Process Explorer , as this tool is much more advanced.