Been running CIS6 here with minor issues, it will be different on everyone's system and environments. Issues i have had so far with it are mainly related to sandboxing Browsers. Sandboxing IE, and trying to watch netflix, seems silverlight does not like this and will "freeze" the browser. As of yesterday, and new version of Comodo Dragon was released following the Chromium build, and it appears to have some glitches as well, especially sandboxed on my machine. But over all performance and protection of the main suite, i would say is stable enough to use and trust.