User Account Control (UAC) is an essential tool for securing Windows systems because it prevents malicious software attempting to start automatically, to apply changes to the system.
So it is important that it is enabled.
Glary Utilities, in some contexts and configurations, may cause damage to the operating system and, like most optimization tools, don't brings benefits in terms of system performance.
CCleaner is more than enough.
The advice of
@jamescv7 about the VM or light virtualization is very important if you play with malware, even if the ideal situation would be a dedicated PC without any personal data inside.