thanks for sharing your config! remove either malwarebytes or zemana anti logger from realtime protecting to reduce change overlap in protection or slowdowns / bsods. you can further harden defender , which by itself on standard settings is quite weak , by using this tool created by Andy Ful called : configure defender here :
AndyFul/ConfigureDefender
download and install NVT osarmor to reduce the attack surface of your system and harden the os! REMOVE system mechanic ASAP! it does more damage thatn good!! ad https everywhere , netcraft anti phising , privacy possum , idn safe and decentraleyes as browser extensions. get simple dnscrypt to harden your browser traffic.