Sandboxie... I have to test, but I would think it would - but only if properly configured. Sounds familiar, right ?
With Sandboxie there is a lot of configuration possible... like Comodo. So I would be surprised if advanced configured "Secure" box did not protect.
I have to find script sample again... I lost it... Hee, hee...
IF there is bypass, of course I would let SBIE know about it by giving Invincea the script. Whether they can, or will, fix it is an entirely different matter.
Default Sandboxie box, I think, will not protect...