Yes, IObit Software is safe to use. Remember to download from their website, or another trusted mirror. When installing be aware of what may be bundled in the installer, ie. Adware (toolbar) may be presented.
For more product details and Free vs Pro Comparison: http://www.iobit.com/driver-booster.php
I recommend learning to you use your computer, by updating drivers by the built-in updater provided by the hardware manufactures. That way you learn about how often updates are released, download size, any Beta updates, changelog information etc.
Remember to check before installing any recommended Drivers by these types of software, as they may not always be providing accurate information, and possible to cause more issues.
I have used both and can I personally feel that Slim Drivers is better at doing its job, but I can honestly say that DB was safe wen I used it about a year or so ago. As we all know, all Iobit free versions try to "convince" you into buying their products, but in no way was I ever infected by any crapware/malware.
There are other options out there, which do a great job: Driver Pack Solution and Sam Drivers are great pieces of software, which I personally have been using ever since I stopped using Slim Drivers and DB.
Hybrid-Analysis and Reverse-It services use the same sandbox as far as I am aware; there's also Malwr which relies on Cuckoo. However, as with all these online sandboxing services, false positives occur, and you still require to have a trained eye to make sense of the logs properly.
The report details you posted actually indicate the opposite from the threat verdict, because it's being flagged as unwanted on VirusTotal, not as malicious software. The unwanted status is opinionated; some people may want to use the software and it isn't actually malicious.
IObit products aren't malware, they are safe, however as with all system optimisation utilities, you need to take good care with what you consent for them to clean otherwise you can cause issues with your system (do more hassle than good). For example, I'd avoid registry cleaning. Cleaning of the temp folder and recycling bin, and un-needed logs which are taking up space? More reasonable with less potential for issues to arise.
It will be a full Pro license. Driver Booster is regularly available as a giveaway. Also, there is no limited trial version. The free version of DB is fully functional, but has less features than the Pro version.