The security related Event ID's that you need to make Custom Views for are below. When you define a custom view, you can just click on it to list out occurances of that particular event ID.
Learn more about: Appendix L: Events to Monitor
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For instance, when a malware tries to install a service, it generates a 4697 event ID.
And when malware makes a new scheduled task, it generates a 4698 event ID.
You need to periodically examine your logs to make sure nothing has gotten thru. Anti-malware detection can Fail. All the malware-writer has to do is tweak his code a little, and it will escape automatic detection.