I have had Winpatrol installed on any personal system that I've owned for years, but I personally don't think of it as any sort of anti-malware application but instead as a useful utility.
As Cats-4 (God, I LOVE that picture!!!!!) has mentioned, WP is really good at both alerting to, listing, and allowing one to deal with any startup items that exist on one's system. Often a service from a valid application can cause system issues; WP provides an elegant way to deal with this.
Now for the truth- I enjoy having Scotty sitting in the Taskbar.
(Tony- Yes, Bill P sold WP to Ruiware this past June (at least I think it was in June).