Real Time Protection:
If you are looking for a light and good security config , start first by trying CIS 5.8 (FREE ) or NIS 2012 (PAID) ... Both have some interesting security features which should give you a high degree of security....
- Comodo Internet Security - Download CIS 5.8
OR
- Norton Internet Security 2012 - Download 90 day FREE trial
Additional on-demand scanner:
Hitman Pro (Trial) -
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An on-demand scanner using multiple anti-malware engines and cloud technology. It offers unlimited free scanning but once you use it to remove detected malware it switches to a 30-day trial version. I recommend using it after you've scanned your hard-drive with the other products you have installed.
Malwarebytes Anti-Malware Free (Free) -
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Malwarebytes Anti-Malware Free utilizes Malwarebytes powerful technology to detect and remove all traces of malware including worms, trojans, rootkits, rogues, dialers, spyware and more.
Additional browser plugins
Adblock Plus for Google Chrome (Free) -
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Adblock Plus for Google Chrome is a content-filtering extension for Google Chrome. Adblock allows users to prevent page elements, such as advertisements, from being downloaded and displayed.
LastPass (Free) -
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LastPass is an online password manager and form filler that makes web browsing easier and more secure.
WOT (Free) -
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To help you avoid malicious sites you can use Web of Trust (WOT) a website rating browser plugin. After you add it to your browser make sure you only visit websites rated "Green" by WOT
Extra protection:
EMET 2 (Enhanced Mitigation Experience Toolkit) (Free) -
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EMET provides users with the ability to deploy security features built into Windows to arbitrary applications. This helps prevent vulnerabilities in those applications from successfully being exploited. DEP, SEHOP and ASLR are such security features, if you want to learn more about what they do, you can watch this
video from Microsoft TechCenter. To configure EMET you should follow this
guide by rationallyPARANOID.
VTUploader (Free) -
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To upload a file to VirusTotal, you can visit the main analysis site, click the Browse button to select a file from your hard drive, and then click the Send file button. You can make this process even easier with the free VirusTotal Uploader utility. After installing it, you can simply right-click any file under 20MB and choose "VirusTotal" from the Send To Windows menu. The scan results will display in your browser as usual.