I always custom install thing so never had anything but pure hips/firewall /av from Comodo, and I also don't mind getting prompts for being set tight.
Defraggler is enough for me since my system disk is SSD so I use it just for data disks form time to time.
I have a big collection of programs that I use for myself and friends and family when setting their systems so I have all of programs you mentioned but since my system is clean and works perfectly as it is now I don't have them installed on my machine.
BTW. for others, depending on their knowledge (and my availability) I set up different security setups since not all are comfortable with popups asking them what to do when unknown program is started or something. I usually like to prepare them something like Avast/Panda/360 TSE, Unchecky, MBAE, MBAM and Zemana on demand, Firefox with Ublock origin and HTTPS everywhere, CCleaner for light maintenance. This setup proved to bu sufficient for now since I don't get so many calls anymore