AFAIK there is no real-time AV protection for Linux. You can install Clam and ClamTK (it is the GUI), if you want, in order to do periodic scans. It is optional.
Most important thing is to be careful of sources for software you install. Anything in the official repository is safe. Anything else, you need to be cautious. Often it will require you to add a PPA (third-party repository for a specific software), and that means you are vulnerable to anything that happens to the PPA, because it will feed updates to your system.