It depends on how you intend to use Sandboxie. If you just use it to test suspicious files like myself, then there really isn't any alternatives.
If you intend to use it for protection there are a few alternatives.
1. Don't download suspicious files and always pay attention to UAC prompts, never approve anything that you are not sure about. Download all of your files from a trusted download site like
Softpedia that checks files for malware. Keep your software updated.
2. Create a limited user account with no admin rights on Windows, only use you admin account to install and update trusted programs. Use your limited user account for everything else.
3. Disable the ability to download files on all of your browsers, use a program like
DDownloads which only list trusted files.
4. Use WinPatrol Free which will block the most common infections since most will require to run at system startup, add drivers, scheduled tasks or services in order to successful. WinPatrol also protects changes to Internet Explorer which most infections will try to change.
5. Always keep your important files backed up because sometimes mistakes will happen.
Enjoy!!