Older versions of TuneUp Utilities were very good. The 2009 version was probably the best. But newer versions are just full of bloated crap.
I never like to have any system maintenance tools that add a lot of processes and services to Windows startup. That just adds a negative performance to your system. I always avoid automatic system maintenance tools, they can do a lot more damage than good for a system.
When it comes to iolo products, avoid them all because they are crap.
Read commits at WOT, they promote scareware products they have an negative impact on your system and cause severe system errors.
iolo is much worse than Uniblue.
Advanced SystemCare Personal (freeware) is one of the best system maintenance tool. CCleaner is the best system cleaner and Tweak Me! (freeware) is one of the best system tweakers.
Never buy these kind of programs, the freeware alternatives are much better and safer.