FYI I installed Portmaster, rebooted, did the setup left it at default settings, and it broke my internet connection, nothing would connect then got a blue screen, rebooted again, and Brave browser was working but very slow, Edge could not connect to any website at all. I played around with it for about a half hour and could not get Edge to connect, had to give up for now and uninstall it.
I will try it again when I have more time, from what I have been reading the SPN can be set per app, so one can have specific browsers use it, and other browsers bypass it, almost like split tunneling where the browsers you use for banking, shopping, crypto transactions, social media etc.., connect normally and browsers for everything else can go through the SPN.