Hmm which ads?..
I don't see ads:
- in Firefox 52.7.3 have Policy Control (stopped 8 items) and before all: 3PRB (stopped 16, digit "16" on the icon) on "Mueller told..." page.
- in first Nightly (Basilisk) have Policeman, so all 3rd party requests are blocked...
- in another Nightly (Basilisk) have Policy Control and 3P Request Blocker too, so nothing, no ads...
- on "Go anime" nothing is animated here, with these add-ons, extensions.
- you see, I don't use signatures, but request blockers here...
All signatures based solutions are outdated, obsolete, old-fashioned, I think...
EDIT:
I see now, that I use too on my all Chrome forks (Slimjet, Cent, Iron) ZenMate Web Firewall, which is forked from uBlock Origin...it's this one which block ads on my Chrome forks...so no ads.