One thing not mentioned enough for average users that try Voodooshield, is that the system needs to not have malware present when installing on the machine for the first time. As it takes a snapshot at that time of installation to "allow" everything on the system to run without issues.
By Default when you do first place it on, it will be placed into Smart Mode, if you have not changed any of the settings and placed it on as "out of the box" this is the mode you will be currently in and it utilizes the white list. The free version which is capable of keeping you safe, is restricted by lack of access to settings, if you are to keep and use it, I would recommend going ahead and getting the license for more granular control.
As for VT Uploader, I have not had my system without this utility in a long time, it is just too handy. Also for Google Chrome there is an extension "VT Chromizer" which places a VT extension in the browser and allows you to scan search links as well as whole web pages, this also has been on my system for some time.
There are many means of securing a system, combinations ect, it will depend on you, your knowledge and uses of your machine on what you settle with, so opinions of what others think you should run are pointless as you need to be happy with your set up. A good portion of security relies on this and learning better "safe surfing habits".
Last but not least, System and Personal Data back ups are a must should any of the above fail you.
Hope this helps.