I'm in a good situation right now. I can wipe my machine and be back up and running in about an hour should the virtualization fail.
90% of my stuff is stored on Sync.com, even with Sync's ridiculously good security, encryption and zero knowledge architecture. (3-Layer Encryption, SOC-1 Data Centers, Zero Knowledge, TFA) I still pre-encrypted everything that goes into it with an AES256 and Blowfish combo. Good luck breaking all of that. But this allows me to essentially rebuild my system from scratch in about an hour. The other 10% is stored on encrypted USB-Sticks for local access.
I'm building a new Ryzen 7 productivity machine on Friday w/32GB DDR4 3200 and the new m.2 32Gb/s SSD Drive. When I finish that will be running Windows with 2 VM's and my surfing/productivity/email/business will be done in one of the VM's on a secure OS with a nested VPN on the spoofed NIC. The horsepower will be there to keep those VM's up and loaded with each machine boot.
I've made significant advances in my security/privacy over the last few months and I am not finished yet.