Generally, disabling that rule is not recommended. It can be especially important in organizations and businesses, where the malware can attack the user from the local network with administrative rights. Next it can attack lsass.exe to steal credentials, admin passwords, etc.
With H_C settings, the malware originated by the user actions can hardly elevate, because it will be first blocked by H_C settings (default-deny). So, in this special configuration in the home environment, disabling that ASR rule can be more beneficial than the danger of broken updates.